MethodsThe anti-inflammatory effect was determined with the models of the swelling of mouse ear, the rat carrageenin paw edema, adjuvant arthritis and the cotton ball like granuloma of mouse. 方法建立小鼠耳廓肿胀、大鼠足跖肿胀、佐剂性关节炎和棉球肉芽肿炎症模型,研究其抗炎作用;
The anti-inflammatory action was studied in mouse ear swelling test and capillary permeability test and anti-coagulation action in mice was also observed by mouse blood coagulation time test. 以小鼠凝血时间测定法进行抗凝血作用研究。结果:续断不同炮制品均具镇痛、抗炎及抗凝血作用。
Results: Hong She analgesic solution had markedly suppressing effect on swelling of mouse ear and footpad in rat. 结果:红蛇定痛液对鼠耳肿胀及大鼠足肿胀均有明显的抑制作用。
Methods: The models of mouse ear tumefaction caused by xylene and rat foot tumefaction caused by carrageenan were used to observe the anti-inflammatory action of YGLDG via oral adiminstration. 方法:给动物灌服药物,采用小鼠耳肿胀法、大鼠足肿胀法、小鼠扭体法、热板法和离体豚鼠胆囊试验观察药物的作用。
To evaluate the effect of Belamcanda chinensis extract on rat paw swelling, mouse ear edema and analgesia activity. 研究射干提取物对实验性大鼠足肿胀、小鼠耳肿胀及小鼠疼痛的影响。
Using the models of dimethylbenzene-induced mouse ear swelling, the anti-inflammatory effect of alkaloids was evaluated. 用二甲苯诱发小鼠耳肿胀动物模型,观察生物碱的抗炎作用。
Methods Analgesia and anti-inflammatory effect were induced by mouse hot plate, acetic acid stretching experiment and mouse peritonitis, mouse ear swelling model. 方法采用小鼠热板、小鼠醋酸扭体实验比较镇痛作用;用小鼠急性腹膜炎、小鼠耳肿胀模型比较抗炎作用。
The swelling experiment of mouse ear induced by xylene confirmed the anti-inflammation activity of I. 小鼠耳肿胀实验证实I具有抗炎活性。
[ Methods] The anti-inflammatory effects were investigated on mouse ear swelling induced by xylene, carrageenin-challenged paw edema, turpentine-elicited nitrogen pouch granuloma and acetic acid-caused air pouch synovitis in rats, respectively. 【方法】采用二甲苯致小鼠耳廓肿胀、角叉菜胶致大鼠足跖肿胀、松节油致大鼠气囊肉芽肿和醋酸造成大鼠气囊滑膜炎的炎症模型观察Cu-Asp抗急、慢性炎症效应;
RESULT: Both Liquids relieved the mouse ear swelling, reduced capillary permeation, promoted phenol red excretion, prolonged cough latent period and decreased cough times. 结果:2药均能明显减轻小鼠耳肿胀、降低毛细血管通透性、促进酚红排泌、延长咳嗽潜伏期和减少咳嗽次数。
In vivo experiment, allografting of cardiac tissue into mouse ear, and in vitro experiment, mixed lymphocyte reaction was used to investigate the effect of naltrexone, an antagonist of opioid receptor, on transplantation rejection. 以小鼠心肌组织异位移植和混合淋巴细胞反应为整体和离体模型,观察了阿片受体阻断剂纳曲酮对移植排异反应的影响。
Result: DAE could inhibit the mouse ear edema induced by dimethylbenzene, inhibit the rat foot swelling induced by carrageenin, and increase the mice pain threshold induced by hot plate. 结果:大泡通乙醇提取物能显著抑制二甲苯所致小鼠耳肿胀及角叉菜胶致大鼠足肿胀,提高热板法小鼠痛阈值。
In vivo experiments, EGCG inhibited edema induced by TPA in mouse ear. 在整体实验,EGCG可以抑制TPA诱导的小鼠耳部水肿。
Results: HTQP suppressed the swelling of mouse ear induced by croton oil, the edema of rat hind paw induced by carrageenan and the increase of peritoneal capillary permeability induced by HAC in mice. 结果:胡桃青皮对巴豆油所致的小鼠耳壳肿胀、大鼠角叉菜胶性足肿胀、醋酸引起的小鼠腹腔毛细血管通透性增高均有明显的抑制作用;
The anti inflammatory effect of Jin's hemorrhoids ointment were observed by using the mouse ear inflammation model induced by xylol and the mouse peritoneal capillary permeability increase model induced by acetic acid. 采用二甲苯引起的小鼠耳廓肿胀及醋酸所致小鼠腹腔毛细血管通透性增高模型,观察金氏痔疮膏的抗炎作用;
Models of acute inflammatory reactions of xylene-induced mouse ear edema and H~+-induced mouse capillary permeability enhancement were performed to study the anti-inflammatory effects. 采用二甲苯、H+等致炎因子引起的小鼠急性渗出性炎症,研究其抗炎的作用。
METHOD Models of acute inflammatory reactions of xylene induced mouse ear edema, albumin induced rat paw edema and the chronic inflammatory reaction of paper induced rat granuloma were performed to study the anti inflammatory effects. 方法用二甲苯致小鼠耳肿胀、鸡蛋清致大鼠足爪肿胀及大鼠肉芽肿炎症模型(纸片法),考察绿舒筋多糖的抗炎作用;
Effect of heparin with low-molecular weight on the mouse ear microcirculation in vivo 小鼠耳廓微循环活体观察低分子量肝素对微循环的影响
Results Zhitong-Zhichuang suppository significantly inhibited the mouse ear edema and the edema of rat granuloma. 结果止痛痔疮栓有明显的抑制小鼠耳肿胀和大鼠肉芽肿作用;
Mouse ear swell induced by dimethybenzene, The sedative effect was studied by pentobarbital sleeping time in mice. 用戊巴比妥钠对小鼠睡眠时间的影响实验,观察其镇静作用;
Results AA injection markedly inhibited acute inflammatory ear swelling following dimethylbenzene stimulation on mouse ear; 结果亚砷酸注射液对二甲苯诱发的小鼠耳急性炎性耳肿胀有显著抑制作用;
In in vivo experiments, GTE inhibited edema induced by TPA in mouse ear. The inhibitory effect of GTE on the induction of ornithine decarboxylase activity was also found in mouse skin treated with TPA. 体内实验表明,GTE可以抑制TPA诱导小鼠耳皮肤水肿,并抑制TPA诱导小鼠皮肤乌氨酸脱羧酶活性增高。
Methods The inflammatory models of mouse ear edema induced by xylene and rat paw edema caused by carrageenin were adopted. 方法应用二甲苯致鼠耳肿胀和角叉菜胶致大鼠足爪肿胀炎症模型。
Methods Model of the swelling of mouse ear, lymphocyte proliferation response and acute toxicity test were used. 方法鼠耳肿胀法、小鼠脾淋巴细胞增殖法、小鼠ig急性毒性试验(最大耐受量测定)。
The mouse ear swelling test can determine the inflammatory swelling and calculate the inhibition rate of swelling. 小鼠耳肿胀实验测定炎性肿胀度并计算肿胀度抑制率。
By xylene-induced mouse ear edema model and the NO inflammation model, the extraction and polarity fraction of the anti-inflammatory activity were screened, and the ethyl acetate was found to be the active fraction. 3. 以二甲苯致小鼠耳肿胀模型和NO炎症模型,对楮实子总提物和各极性部位进行抗炎活性筛选,筛选出乙酸乙酯部位为楮实子的活性部位。
KG ointment can inhibit xylene-induced mouse ear inflammation and 2,4-dinitrofluorobenzene-induced delayed-type of hypersensitivity in mice, can improve the infiltration of ear tissue inflammatory cells, and reduce cell swelling, which indicates that KG ointment has efficacy in the treatment of acute eczema. 2. 结论:1.KG软膏能抑制二甲苯诱发的小鼠耳廓炎症反应,2,4-二硝基氟苯诱发的小鼠迟发型超敏反应、改善耳组织炎细胞浸润情况、减轻细胞间水肿,表明KG软膏有治疗急性湿疹的作用。
The influence of ISA on the acute phase of inflammation was evaluated using the xylene-induced mouse ear inflammatory model and the agar-induced rat hind paw edema model. 采用二甲苯小鼠耳廓炎症模型和琼脂足肿胀急性炎症模型,观察ISA对炎症急性时相的影响。